Protein: Q8WV44 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q8WV44 (Uniprot)	TRI41_HUMAN	TRIM41	E3 ubiquitin-protein ligase TRIM41	human	No

Protein Function

Uniprot: Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C.

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0006139	nucleobase-containing compound metabolic process	63, 572	GO:0033036	macromolecule localization	748	4.58e-19	9.70e-72
GO:0044260	cellular macromolecule metabolic process	127, 340, 649, 661	GO:0033036	macromolecule localization	748	4.56e-06	3.25e-28

MoonDB Network Modules

Biological Processes

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Module ID (MoonGO)	GO ID (BP)	GO Name
63	GO:0010467	gene expression
63	GO:0090304	nucleic acid metabolic process
63	GO:0060255	regulation of macromolecule metabolic process
80	GO:0051252	regulation of RNA metabolic process
80	GO:0010468	regulation of gene expression
127	GO:0016070	RNA metabolic process
127	GO:0010467	gene expression
151	GO:0060255	regulation of macromolecule metabolic process
160	GO:0006355	regulation of transcription, DNA-templated
191	GO:0006355	regulation of transcription, DNA-templated

Cellular Components

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Module ID (MoonGO)	GO ID (CC)	GO Name
63	GO:0005634	nucleus
80	GO:0005634	nucleus
84	GO:0005634	nucleus
89	GO:0005634	nucleus
127	GO:0005634	nucleus
151	GO:0005634	nucleus
160	GO:0005634	nucleus
190	GO:0005829	cytosol
190	GO:0043232	intracellular non-membrane-bounded organelle
191	GO:0031981	nuclear lumen

Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0016567	protein ubiquitination	IEA

Cellular Components

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No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

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Publications Associated

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PMID	Article Title
11549288	M phase-specific association of human topoisomerase IIIbeta with chromosomes.
14702039	Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15498874	Large-scale cDNA transfection screening for genes related to cancer development and progression.
16022281	Intracellular localization and domain organization of human TRIM41 proteins.
17893151	Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase.
20068231	Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
24275569	An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
25218447	Uncovering global SUMOylation signaling networks in a site-specific manner.

OMIM Diseases Associated

No results found.

Protein Domains Associated

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