Protein: P60010 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
P60010 (Uniprot)	ACT_YEAST	ACT1	Actin	yeast	No

Protein Function

Uniprot: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

MoonDB Dissimilar Functions

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0097435	supramolecular fiber organization	1242	GO:0006725	cellular aromatic compound metabolic process	962	4.17e-09	4.54e-39

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MoonDB Network Modules

Biological Processes

Showing 1 to 8 of 8 entries

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Module ID (MoonGO)	GO ID (BP)	GO Name
962	GO:0006139	nucleobase-containing compound metabolic process
1093	GO:0022607	cellular component assembly
1242	GO:0051666	actin cortical patch localization
1242	GO:0007015	actin filament organization
1242	GO:0034622	cellular macromolecular complex assembly
1242	GO:0006897	endocytosis
1242	GO:1903047	mitotic cell cycle process
1242	GO:0032505	reproduction of a single-celled organism

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Cellular Components

Showing 1 to 3 of 3 entries

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Module ID (MoonGO)	GO ID (CC)	GO Name
914	GO:0043232	intracellular non-membrane-bounded organelle
1093	GO:0043232	intracellular non-membrane-bounded organelle
1242	GO:0030479	actin cortical patch

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Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0000001	mitochondrion inheritance	TAS
GO:0000011	vacuole inheritance	IMP
GO:0000132	establishment of mitotic spindle orientation	TAS
GO:0000916	actomyosin contractile ring contraction	IMP
GO:0001300	chronological cell aging	IMP
GO:0006281	DNA repair	IDA
GO:0006887	exocytosis	TAS
GO:0006897	endocytosis	IMP
GO:0007119	budding cell isotropic bud growth	TAS
GO:0009306	protein secretion	IMP

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Cellular Components

Showing 1 to 7 of 7 entries

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0000142	cellular bud neck contractile ring	IDA
GO:0000812	Swr1 complex	IDA
GO:0005884	actin filament	IDA
GO:0030479	actin cortical patch	IDA
GO:0031011	Ino80 complex	IPI
GO:0032432	actin filament bundle	IDA
GO:0035267	NuA4 histone acetyltransferase complex	IDA

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

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Interactor	Also a MoonDB EMF protein
AIP1_YEAST	No
BEM1_YEAST	No
BNI1_YEAST	No
BUD6_YEAST	No
CAP_YEAST	No
COFI_YEAST	No
DLD2_YEAST	No
FIMB_YEAST	No
FUS1_YEAST	No
HXKG_YEAST	No

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Publications Associated

Showing 1 to 10 of 18 entries

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PMID	Article Title
1885608	Unusual metabolism of the yeast actin amino terminus.
1935913	Site-directed mutagenesis of the yeast actin gene: a test for actin function in vivo.
6096014	Lariat structures are in vivo intermediates in yeast pre-mRNA splicing.
6286825	The nucleotide sequences of the actin genes from Saccharomyces carlsbergensis and Saccharomyces cerevisiae are identical except for their introns.
6994099	Structure of a split yeast gene: complete nucleotide sequence of the actin gene in Saccharomyces cerevisiae.
7001447	Isolation and sequence of the gene for actin in Saccharomyces cerevisiae.
7003553	Molecular cloning of the actin gene from yeast Saccharomyces cerevisiae.
7670463	Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae.
8935650	Protein expression during exponential growth in 0.7 M NaCl medium of Saccharomyces cerevisiae.
11491363	Partial sequence analysis of the actin gene and its potential for studying the phylogeny of Candida species and their teleomorphs.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 10 of 12 entries

Search:

Domain Name	Domain ID	Source
Actin	IPR004000	InterPro
Actin	PF00022	Pfam
ACTIN	PR00190	PRINTS
ACTIN	SM00268	SMART
Actin/actin-like_CS	IPR020902	InterPro
Actin_CS	IPR004001	InterPro
ACTINS_1	PS00406	PROSITE
ACTINS_2	PS00432	PROSITE
ACTINS_ACT_LIKE	PS01132	PROSITE
ATBY	A03005	PIR

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